Hilton is sitting with chest and hamstring injuries. Tight end Jack Doyle is also out with a hip issue, along with running back Marlon Mack (hamstring), tackle Denzelle Good (personal matter) and cornerback Kenny Moore II (concussion).
Patriots cornerback Eric Rowe is sidelined for the third straight week with a groin injury. Fellow cornerback and recent acquisition Cyrus Jones is also out with an unknown ailment.
Tight end Rob Gronkowski will play after being limited for part of the practice week with an ankle injury. He left the second half of the Patriots’ win over Miami last week after aggravating the injury.
Colts: TE Jack Doyle, T Denzelle Good, WR T.Y. Hilton, RB Marlon Mack, CB Kenny Moore II, DT Hassan Ridgeway, CB Quincy Wilson.
Patriots: OL Cole Croston, OL Ted Karras, CB Eric Rowe, CB Cyrus Jones, DL Geneo Grissom, DE Derek Rivers, DL Keionta Davis.